Clinical Aspects of Tardive Dyskinesia

Epidemiology, Natural History, and Management
  • George Gardos
  • Jonathan O. Cole


Public awareness often seems to lag behind the appearance of a phenomenon by several years. The history of tardive dyskinesia (TD) is a good example. Although the first reports of the syndrome started to appear in the early 1960s, it was not until the late 1960s and early 1970s that the psychiatric profession became aware of the existence of the condition. As the literature began to swell with ever-increasing numbers of reports on TD during the 1970s, there was gradually increasing concern over this apparently iatrogenic condition, which has created alarm over the use of neuroleptics. The pendulum may be starting to swing back in response to recent reports which suggest that TD is not always irreversible, and that the prognosis is usually better than was at first feared. This chapter will provide an overview of the prevalence, course, prognosis, and management of TD. Because of the enormous amount of relevant research data, the literature review will be selective.


Tardive Dyskinesia Fusaric Acid Neuroleptic Treatment Abnormal Involuntary Movement Scale Orofacial Dyskinesia 
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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • George Gardos
    • 1
  • Jonathan O. Cole
    • 2
  1. 1.West-Ros-Park Mental Health CenterBostonUSA
  2. 2.Psychopharmacology ServicesMcLean HospitalBelmontUSA

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