Adrenocorticosteroid Drugs

  • John A. Thomas
  • Edward J. Keenan


The adrenocorticosteroids drugs are an important group of therapeutic compounds used for a variety of clinical purposes. It is estimated that annually at least 5 million patients in the United States receive adrenocortical steroids. These agents are used in hormonal replacement therapy as well as for extension of their physiological actions. The adrenocorticosteroids are well recognized for the diversity of their actions underlying their extensive therapeutic use. It is the anti-inflammatory and immunosuppressive activity produced by these steroids that is widely sought for the palliative therapy of many clinical conditions. As would be expected of drugs that influence a multiplicity of tissues, the adrenocortical steroids produce a number of adverse effects. A well-founded appreciation for the pharmacological characteristics of these drugs provides the basis for the rational and safe use of this important group of drugs.


Adrenal Gland Glucocorticoid Receptor Congenital Adrenal Hyperplasia Glucocorticoid Therapy Status Asthmaticus 
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Recommended Readings

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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • John A. Thomas
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
  • Edward J. Keenan
    • 7
    • 8
    • 9
    • 10
  1. 1.Corporate ResearchTravenol Laboratories, Inc.Round LakeUSA
  2. 2.Department of PharmacologyNorthwestern University School of MedicineChicagoUSA
  3. 3.Department of UrologyNorthwestern University School of MedicineChicagoUSA
  4. 4.Department of Pharmacology and ToxicologyWest Virginia School of MedicineMorgantownUSA
  5. 5.Department of PharmacologyUniversity of Illinois School of MedicineChicagoUSA
  6. 6.Department of PharmacologyRush-Presbyterian School of MedicineChicagoUSA
  7. 7.Hormone Receptor Laboratory, School of MedicineThe Oregon Health Sciences UniversityPortlandUSA
  8. 8.Department of Surgery, School of MedicineThe Oregon Health Sciences UniversityPortlandUSA
  9. 9.Department of Pharmacology, School of MedicineThe Oregon Health Sciences UniversityPortlandUSA
  10. 10.Department of Medicine (Medical Oncology), School of MedicineThe Oregon Health Sciences UniversityPortlandUSA

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