Construction of Protein Databases for Comparison of Normal and Transformed Cells

  • James I. Garrels
  • B. Robert FranzaJr.
Part of the NATO ASI Series book series (NSSA, volume 91)


Transformation of cultured cell lines and primary cells can be achieved by defined agents including cloned viral genes and activated cellular oncogenes. The transformed cell is recognized by its altered morphology and relaxed growth regulation in culture, and not necessarily by its tumorigenicity. Relationships between some of the oncogene products and biochemical pathways of growth regulation are just beginning to emerge.


Proliferate Cell Nuclear Antigen Standard Pattern Oncogene Product Cellular Oncogene Database Approach 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • James I. Garrels
    • 1
  • B. Robert FranzaJr.
    • 1
  1. 1.Cold Spring Harbor LaboratoryCold Spring HarborUSA

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