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Glycolipid Antigens: Potential in Cancer Detection and Diagnosis

  • Gary R. Matyas
  • Vivian P. Walter-Doelling
  • Christine Ferroli
  • Kenneth R. Pennington
  • Diane Pikaard
  • D. James Morré
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 15B)

Abstract

A number of tumour-specific monoclonal antibodies (MAb’s) have been produced which are directed to unique carbohydrate structures associated with cellular membranes as glycolipids rather than glycoproteins (as reviewed by S.-I. Hakomori [1]). The potential of other more common glycolipid antigens for use in cancer detection and diagnosis is now addressed with especial emphasis on a specific role in early detection. The assays now reported concern glycolipids in sera from hepatocarcinogen-fed rats and cancer patients.

Keywords

Sialic Acid Serum Sialic Acid Total Ganglioside Glycolipid Antigen Neutral Glycosphingolipids 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Gary R. Matyas
    • 1
  • Vivian P. Walter-Doelling
    • 1
  • Christine Ferroli
    • 1
  • Kenneth R. Pennington
    • 1
    • 2
  • Diane Pikaard
    • 1
  • D. James Morré
    • 1
  1. 1.Purdue Cancer CenterPurdue UniversityWest LafayetteUSA
  2. 2.Arnett ClinicLafayetteUSA

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