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Investigation and Exploitation of Antibody Combining Sites pp 267–274Cite as

The T-Cell Receptor

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Part of the book series: Methodological Surveys in Biochemistry and Analysis ((MSBA,volume 15B))

Abstract

Use has been made of monoclonal antibodies (MAb’s) that appear to recognize all or part of the T-cell receptor, features of which are discussed. We have devised a new approach to receptor specificity investigation, and encountered problems that are discussed. We consider the contribution of α and β chains to T-cell specificity, and the expression of T-cell receptors on thymocytes.

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Author information

Authors and Affiliations

  1. Department of Medicine, National Jewish Hospital & Research Center, 3800 East Colfax Avenue, Denver, CO, 80206, USA

    Phillipa Marrack, Kathryn Haskins, Neal Roehm, Janice White, Willi Born, Jordi Yagüe, Edward Palmer & John W. Kappler

Authors
  1. Phillipa Marrack
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  2. Kathryn Haskins
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  3. Neal Roehm
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  4. Janice White
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  5. Willi Born
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  6. Jordi Yagüe
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  7. Edward Palmer
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  8. John W. Kappler
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Editor information

Editors and Affiliations

  1. Guildford Academic Associates, Guildford, UK

    Eric Reid

  2. University of Cambridge, Cambridge, UK

    G. M. W. Cook

  3. Cancer Center, Purdue University, West Lafayette, Indiana, USA

    D. J. Morré

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© 1985 Plenum Press, New York

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Marrack, P. et al. (1985). The T-Cell Receptor. In: Reid, E., Cook, G.M.W., Morré, D.J. (eds) Investigation and Exploitation of Antibody Combining Sites. Methodological Surveys in Biochemistry and Analysis, vol 15B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5006-4_30

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  • DOI: https://doi.org/10.1007/978-1-4684-5006-4_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5008-8

  • Online ISBN: 978-1-4684-5006-4

  • eBook Packages: Springer Book Archive

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