Abstract
The majority of neurons and glial cells in the mammalian CNS develop from the neuroepithelial cells that form the neural tube. But what is the lineage relationship between these different cell types and what determines whether an individual neuroepithelial cell becomes a particular type of neuron or one of the several types of glial cells?
This Forum Abstract is supplemented, in respect of approaches, by an Editor’s précis, not by author’s text (it had been agreed that none would be furnished).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Illustrative publications
Raff, M.C., Abney, E.R., Cohen, J., Lindsay, R. & Noble, M. (1983) Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides and growth characteristics. J. Neuroscience 3, 1289–1300.
Raff, M.C., Miller, R. & Noble, M. (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on the culture medium. Nature 303, 390–396.
Miller, R.H. & Raff, M.C. (1984) Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct. J. Neurosci. 4, 585–592.
d. Raff, M.C., Abney, E.R. & Miller, R.H. (1984) Two glial cell lineages diverge prenatally in rat optic nerve. Dev. Biol. 106, 53–60.
Raff, M.C., Abney, E.R. & Miller, R.H. (1984) Two glial cell lineages diverge prenatally in rat optic nerve. Dev. Biol. 106, 53–60.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Raff, M.C. (1985). An Immunological Approach to the Cell Lineage Problem in the Mammalian CNS. In: Reid, E., Cook, G.M.W., Morré, D.J. (eds) Investigation and Exploitation of Antibody Combining Sites. Methodological Surveys in Biochemistry and Analysis, vol 15B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5006-4_24
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5006-4_24
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5008-8
Online ISBN: 978-1-4684-5006-4
eBook Packages: Springer Book Archive