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Cholinergic-Specific Nerve Terminal Antigens

  • V. P. Whittaker
  • E. Borroni
  • P. Ferretti
  • G. P. Richardson
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 15B)

Abstract

In mammals, transmission of information at synapses depends on >20 chemical transmitters, on which classification of neurones may be based. While the transmitter release mechanism may be common to all presynaptic nerve terminals, the synthesis, storage and eventual disposal of each transmitter require an unknown number of specific proteins. In development, moreover, surface markers specific for the different types of synapse may be needed to regulate synaptogenesis. The ability to recognize transmitter-specific components would be invaluable in developing new morphological methods and for isolating subpopulations of detached nerve terminals (synaptosomes) and their constituent organelles (synaptic vesicles; plasma membranes, p.m.) derived from neurones of defined transmitter type.

Keywords

Synaptic Vesicle Nerve Terminal Electric Organ Discharge Stratum Oriens Presynaptic Nerve Terminal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • V. P. Whittaker
    • 1
  • E. Borroni
    • 1
  • P. Ferretti
    • 1
  • G. P. Richardson
    • 1
  1. 1.Abteilung NeurochemieMax-Planck-Institut für Biophysikalische ChemieGöttingenW. Germany

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