Cholinergic-Specific Nerve Terminal Antigens

  • V. P. Whittaker
  • E. Borroni
  • P. Ferretti
  • G. P. Richardson
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 15B)


In mammals, transmission of information at synapses depends on >20 chemical transmitters, on which classification of neurones may be based. While the transmitter release mechanism may be common to all presynaptic nerve terminals, the synthesis, storage and eventual disposal of each transmitter require an unknown number of specific proteins. In development, moreover, surface markers specific for the different types of synapse may be needed to regulate synaptogenesis. The ability to recognize transmitter-specific components would be invaluable in developing new morphological methods and for isolating subpopulations of detached nerve terminals (synaptosomes) and their constituent organelles (synaptic vesicles; plasma membranes, p.m.) derived from neurones of defined transmitter type.


Synaptic Vesicle Nerve Terminal Electric Organ Discharge Stratum Oriens Presynaptic Nerve Terminal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Fox, G.C., Richardson, G.P. (1978) J. Comp. Neurol. 179, 677–697.CrossRefGoogle Scholar
  2. 2.
    Fox, G.Q., Richardson, G.P. (1978) J. Comp.Neurol. 185, 293–316.CrossRefGoogle Scholar
  3. 3.
    Stadler, H., Tashiro, T. (1979) J. Biochem. 101, 171–178.Google Scholar
  4. 4.
    Whittaker, V.P., Essman, W.B., Dowe, G.H.C. (1974) Biochem. J. 128, 833–845.Google Scholar
  5. 5.
    Ohsawa, K., Dowe, G.H.C., Morris, S.J., Whittaker, V.P. (1979) Brain Res. 161, 447–457.CrossRefGoogle Scholar
  6. 6.
    Walker, J.H., Obrocki, J., Zimmermann, C.W. (1983) J. Neurochem. 41, 209–216.CrossRefGoogle Scholar
  7. 7.
    Stadler, H., Whittaker, V.P. (1978) Brain Res. 153, 408–413.CrossRefGoogle Scholar
  8. 8.
    Stadler, H., Dowe, G.H.C. (1982) E’MBO J. 1, 1381–1384.Google Scholar
  9. 9.
    Walker, J.H., Jones, R.T., Obrocki, J., Richardson, G.P., Stadler, H. (1982) Cell Tiss. Res. 223, 101–116.CrossRefGoogle Scholar
  10. 10.
    Osborne, N.N., Beale, R.,Nicholas, D., Stadler, H., Walker, J.H., Jones, R.T.,Whittaker, V.P. (1982) Cell Mol. Neurobiol. 2, 151–163.CrossRefGoogle Scholar
  11. 11.
    Jones, R.T., Walker, J.H., Stadler, H., Whittaker, V.P. (1982) Cell Tiss. Res. 223, 117–126.Google Scholar
  12. 12.
    Jones, R.T., Walker, J.H., Stadler, H., Whittaker, V.P. (1982) Cell Tiss. Res. 224, 685–688.CrossRefGoogle Scholar
  13. 13.
    Zimmermann, H.,Denston, C.R. (1977) Neuroscience 2, 715–730.Google Scholar
  14. 14.
    Giompres, P.E., Zimmermann, H., Whittaker, V.P. (1981) Neuroscience 6, 765–774.CrossRefGoogle Scholar
  15. 15.
    Giompres, P.E., Whittaker, V.P. (1984) Biochim. Biophys. Acta 770, 166–170.CrossRefGoogle Scholar
  16. 16.
    Jones, R.T., Fox, G.Q. (1982) Abstracts, Eur. Symp. on Cholinergic Mechanisms, Strasbourg (R. Massarelli, organizer), p. 59.Google Scholar
  17. 17.
    Jones, R.T., Walker, J.H., Jones, R.T., Whittaker, V.P. (1982) Cell Tiss. Res. 218, 355–373.Google Scholar
  18. 18.
    Richardson, P.J., Walker, J.H., Jones, R.T., Whittaker, V.P. (1982) J. Neurochem. 38, 1605–1614.CrossRefGoogle Scholar
  19. 19.
    Richardson, P.J. (1981) J. Neurochem. 37, 258–260.CrossRefGoogle Scholar
  20. 20.
    Ferretti, P., Borroni, E. (1984) J. Neurochem. 42, 1085–1093.Google Scholar
  21. 21.
    Ferretti, P., Borroni, E. (1983) Abstracts, Symp. on Ganglio-side Structure Function and Biomedical Potential (held at Island Hall Hotel, B.C., Canada ), p. 62.Google Scholar
  22. 22.
    Young, W.W., Laine, R.A., Hakomori, S.I. (1978) Meth. Enzymol. 50, 137–140.CrossRefGoogle Scholar
  23. 23.
    Tettamanti, G., Bonali, F., Marchesini, S., Zambotti, V. (1973) Biochim. Biophys. Acta 296, 160–170.Google Scholar
  24. 24.
    Miettinen, T., Takki-Lukkainen, I.T. (1958) Acta Chem. Scand. 13, 856–858.CrossRefGoogle Scholar
  25. 25.
    Brockhaus, M., Masnani, J.L., Blaszczyk, M., Stephlewki, Z., Koprowski, H., Karlsson, K.A., Larson, G., Ginsburg, V. (1981) J. BioZ. Chem. 256, 1322–1323.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • V. P. Whittaker
    • 1
  • E. Borroni
    • 1
  • P. Ferretti
    • 1
  • G. P. Richardson
    • 1
  1. 1.Abteilung NeurochemieMax-Planck-Institut für Biophysikalische ChemieGöttingenW. Germany

Personalised recommendations