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Fetal Brain Tissue Transplants Promote Behavioral Recovery from Bilateral Lesions of the Cerebral Cortex in Adult Rats

  • Donald G. Stein
  • Randy Labbe
  • Arthur Firl
  • Holly Rakowski
  • Michael Attella
Part of the Advances in Behavioral Biology book series (ABBI, volume 28)

Abstract

We recently demonstrated that frontal cortex taken from embryonic rats and transplanted directly into the damaged frontal cortex of adult animals, could dramatically improve their performance on a spatial alternation task. Implants of fetal cerebellum had no such effect. Although recovery of function was more rapid in the rats with cortical transplants, they were not able to perform the learning task as well as intact controls. Since the recovery was not complete, we decided to examine some of the factors that could enhance the effectivness of the transplants.

Keywords

Frontal Cortex Functional Recovery Occipital Cortex Bilateral Lesion Intact Control 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Donald G. Stein
    • 1
  • Randy Labbe
    • 1
  • Arthur Firl
    • 1
  • Holly Rakowski
    • 1
  • Michael Attella
    • 1
  1. 1.Department of PsychologyClark UniversityWorcesterUSA

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