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Are Beta Adrenoreceptors Involved in Visuocortical Plasticity?

  • T. Kasamatsu
  • T. Shirokawa
Part of the Advances in Behavioral Biology book series (ABBI, volume 28)

Abstract

In everyday life we adults learn many things, usually with great effort. On the other hand, children sometimes learn a few things very quickly without much effort, performing far better than adults. A good example is learning a spoken language which is different from one’s mother tongue. What can account for this age-dependent difference in learning? What makes performance of the immature brain more efficient than that of the mature one? There is no reason at the moment to believe the presence of totally independent neuronal machinery operating in the two brains. It seems to be practical, however, to treat them separately and devise paradigms which may test likely mechanisms or factors at the cellular level unique to each experimental condition. Thus, changes that occur in neuronal connections in the young brain during early postnatal or posthatching life, namely, critical period plasticity (e.g. Erzurumlu and Killackey, 1982; Kasamatsu, 1983), may be understood as an example of “involuntary learning” by an immature neuronal network during a process of its self-organization. This type of learning is possible for only young individuals and totally depends, within the ground framework defined by genetic constraint, on the sum of “experience” received by them. One cannot help drawing an analogy between critical period plasticity and state-dependent learning in adults.

Keywords

Visual Cortex Locus Coeruleus Striate Cortex Ocular Dominance Monocular Deprivation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Adrien, J., Buisseret, P., Fregnac, Y., Gary-Bobo, E., Imbert, M., Tassin, J.-P., and Trotter, Y., 1982, Noradrenaline et plasticité du cortex visuel du chaton: un reexamen, C.R. Acad. Sci. Paris, 295:745.Google Scholar
  2. Bear, M. F., and Daniels, J. D., 1983, The plastic reponse to monocular deprivation persists in kitten visual cortex after chronic depletion of norepinephrine, J. Neurosci., 3:407.Google Scholar
  3. Bear, M. F., Paradiso, M. A., Schwartz, M., Nelson, S. B., Carnes, K. M., and Daniels, J. D., 1983, Two methods of catecholamine depletion in kitten visual cortex yield different effects on plasticity, Nature, 302:245.CrossRefGoogle Scholar
  4. Blakemore, C., 1978, Maturation and modification in the developing visual system, in: “Handbook of Sensory Physiology VIII: Perception”, H. W. Leibowitz and H.-L. Teuber, eds., Springer-Verlag, Berlin.Google Scholar
  5. Daw, N. W., Rader, R. K., Robertson, T. W., and Videen, T. O., 1983, Do short term and long term depletion of noradrenaline have different effects on visual deprivation in the kitten visual cortex?, Soc. Neurosci. Abstr., 9:1217.Google Scholar
  6. Daw, N. W., Robertson, T. W., Rader, R. K., Videen, T. O., and Coscia, C. J., 1984, Substantial reduction of cortical noradrenaline by lesions of adrenergic pathways does not prevent effects of monocular deprivation, J. Neurosci., 4:1354Google Scholar
  7. Erzurumlu, R. S., and Killackey, H. P., 1982, Critical and sensitive periods in neurobiology, in: “Current Topics in Developmental Biology”, A. A. Moscona, A. Monroy, and R. K. Hunt, eds., Academic Press, New York.Google Scholar
  8. Fregnac, Y., and Imbert, M., 1984, Development of neuronal selectivity in primary visual cortex of cat, Physiol. Rev., 64:325.Google Scholar
  9. Hubel, D. H., and Wiesel, T. N., 1970, The period of susceptibility to the physiological effects of unilateral eye closure in kittens, J. Physiol. Lond., 206:419.Google Scholar
  10. Hubel, D. H., Wiesel, T. N., and Le Vay, S., 1977, Plasticity of ocular dominance columns in monkey striate cortex, Phil. Trans. R. Soc. Lond. B., 278:377.CrossRefGoogle Scholar
  11. Jonsson, G., 1980, Chemical neurotoxins as denervation tools in neurobiology, Ann. Rev. Neurosci., 3:169.CrossRefGoogle Scholar
  12. Jonsson, G., and Kasamatsu, T., 1983, Maturation of monoamine neurotransmitters and receptors in cat occipital cortex during postnatal critical period, Exp. Brain Res., 50:449.CrossRefGoogle Scholar
  13. Kasamatsu, T., 1979, Involvement of the ß-adrenergic receptor in cortical plasticity, ARVO Abstr. Suppl. Invest. Ophth. Vis. Sci., 18:135.Google Scholar
  14. Kasamatsu, T., 1982a, A role of the central norepinephrine system in regulation of neuronal plasticity in cat visual cortex, Biomed. Res. Suppl. 3, in: “Neurotransmitters in the Retina and the Visual Centers”, A. Kaneko, N. Tsukahara, and K. Uchizono, eds., Biomedical Research Foundation, Tokyo.Google Scholar
  15. Kasamatsu, T., 1982b, Enhancement of neuronal plasticity by activating the norepinephrine system in the brain: A remedy for amblyopia, Human Neurobiol., 1:49.Google Scholar
  16. Kasamatsu, T., 1983, Neuronal plasticity maintained by the central norepinephrine system in the cat visual cortex, in: “Progress in Psychobiology and Physiological Psychology”, J. M. Sprague, and A. N. Epstein, eds., Academic Press, New York.Google Scholar
  17. Kasamatsu, T., Itakura, T., Jonsson, G., Heggelund, P., Pettigrew, J. D., Nakai, K., Watabe, K., Kuppermann, B. D., and Ary, M., 1984, Neuronal plasticity in cat visual cortex: A proposed role for the central noradrenaline system, in: “Monoamine Innervation of Cerebral Cortex”, L. Descarries, T. Reader, and H. H. Jasper, eds., Alan R. Liss, Inc., New York.Google Scholar
  18. Kasamatsu, T., and Pettigrew, J. D., 1976, Depletion of brain catecholamines: failure of ocular dominance shift after monocular occlusion in kittens, Science, 194:206.CrossRefGoogle Scholar
  19. Kasamatsu, T., and Pettigrew, J. D., 1979, Preservation of binocularity after monocular deprivation in the striate cortex of kittens treated with 6-hydroxydopamine, J. Comp. Neurol., 185:139.CrossRefGoogle Scholar
  20. Kasamatsu, T., Pettigrew, J. D., and Ary, M., 1979, Restoration of visual cortical plasticity by local microperfusion of norepinephrine, J. Comp. Neurol., 185:163.CrossRefGoogle Scholar
  21. Kasamatsu, T., Watabe, K., Heggelund, P., and Schöller, E., 1985, Plasticity in the cat visual cortex restored by electrical stimulation of the locus coeruleus, Neuroscience Res., (in press).Google Scholar
  22. Kasamatsu, T., Watabe, K., Schöller, E., and Heggelund, P., 1982, Activation of the central noradrenaline system: A remedy for experimental amblyopia, First World Cong. IBRO Abstr., Neurosci. Suppl., 7:S113.Google Scholar
  23. Kostrzewa, R. M., and Jacobowitz, D. M., 1974, Pharmacological actions of 6-hydroxydopamine, Pharmacol. Rev., 62:199.Google Scholar
  24. Korf, J., Roth, R. H., and Aghajanian, G. K., 1973, Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways, Eur. J. Pharmacol., 23:276.CrossRefGoogle Scholar
  25. Movshon, J. A., and Van Sluyters, R. C., 1981, Visual Neural Development, Ann. Rev. Psychol., 32: 477–522.CrossRefGoogle Scholar
  26. Pettigrew, J. D., 1978, The paradox of the critical period of striate cortex, in: “Neural Plasticity”, C. W. Cotman, ed., Raven Press, New York.Google Scholar
  27. Pettigrew, J. D., and Kasamatsu, T., 1978, Local perfusion of noradrenaline maintains visual cortical plasticity, Nature, 271:761.CrossRefGoogle Scholar
  28. Sherman, S. M., and Spear, P. D., 1982, Organization of visual pathways in normal and visually deprived cats, Physiol. Rev., 62:738.Google Scholar
  29. Shirokawa, T., and Kasamatsu, T., 1984, ß-Adreneragic receptor mediates neuronal plasticity in visual cortex, ARVO Abstr. Suppl. Invest. Ophth. Vis. Sci., 25:214.Google Scholar
  30. Tanaka, C., Inagaki, C., and Fujiwara, H., 1976, Labelled noradrenaline release from rat cerebral cortex following electrical stimulation of locus coeruleus, Brain Res., 106:384.CrossRefGoogle Scholar
  31. Watabe, K., Nakai, K., and Kasamatsu, T., 1982, Visual afferents to norepinephrine-containing neurons in cat locus coeruleus, Exp. Brain Res., 48:66.CrossRefGoogle Scholar
  32. Wiesel, T. N., and Hubel, D. H., 1963, Single-cell responses in striate cortex of kittens deprived of vision in one eye, J. Neurophysiol., 26:1003.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • T. Kasamatsu
    • 1
  • T. Shirokawa
    • 1
    • 2
  1. 1.Smith-Kettlewell Institute of Visual SciencesSan FranciscoUSA
  2. 2.School of OptometryUniversity of CaliforniaBerkeleyUSA

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