The Cell Biological Consequences of Passive Avoidance Training in the Chick
In the late 1960s, Pat Bateson, Gabriel Horn and I began to work together on the cell biology of learning and memory, using imprinting in the young chick as a model. Other papers in this volume describe the elegant way in which the imprinting work has been continued by the Cambridge group. Here, I will review the results of the use of an alternative form of early learning in the young chick, based on a one trial passive avoidance task. The point is that, for the biochemist there are certain disadvantages to studying the sequelae of imprinting as a model for memory. The process of training by exposure to the stimulus is a relatively long one, and this makes it harder to distinguish the cellular events associated with putative memory storage processes from those which are the concomitants of the experience of training. Birds also show a degree of variability in their behaviour during training and the strength of their later preference which can be exploited experimentally but which also adds to the complexity of the analysis.
KeywordsPassive Avoidance Forebrain Base Passive Avoidance Task Young Chick Chick Brain
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