Is the Hippocampus Really Involved in Memory?

  • Leonard E. Jarrard
Part of the Advances in Behavioral Biology book series (ABBI, volume 28)


When asked about the functions of the hippocampus, most investigators in the area agree that the hippocampus is involved in some way in memory. A good summary of how many feel was provided by John O’Keefe (1983) in a panel discussion at a recent conference. O’Keefe said, “...there is general agreement or consensus that it (the hippocampus) has something to do with memory and a disagreement as to what kinds of memories” (p. 614).


Dentate Gyrus Place Task Work Memory Error Bilateral Damage Reference Memory Error 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Fink, R. P., and Heimer, L., 1967, Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the CNS, Brain Res., 4:369.CrossRefGoogle Scholar
  2. Gray, J. A., and McNaughton, N., 1983, Comparison between the behavioral effects of septal and hippocampal lesions: a review, Neurosci. Biobehav, Rev., 7:119.CrossRefGoogle Scholar
  3. Green, J. D., 1960, The hippocampus, in: “The Handbook of Physiology,” Vol. II, J. Field, ed., Williams and Wilkins Co., Baltimore.Google Scholar
  4. Gregory, R. L., 1961, The brain as an engineering problem, in: “Current Problems in Animal Behavior,” W. H. Thorpe and O. L. Zangwill, eds., Cambridge University Press, Cambridge.Google Scholar
  5. Horel, J. A., 1978, The neuroanatomy of memory, Brain, 101:403.CrossRefGoogle Scholar
  6. Isseroff, A., Leveton, L., Freeman, G., Lewis, M., and Stein, D. G., 1976, Differences in the behavioral effects of single-stage and serial lesions of the hippocampus, Exptl. Neurol., 53:339.CrossRefGoogle Scholar
  7. Jarrard, L. E., 1976, Anatomical and behavioral analysis of hippocampal cell fields, J. comp. physiol. Psychol., 90:1035.CrossRefGoogle Scholar
  8. Jarrard, L. E., 1983, Selective hippocampal lesions and behavior: effects of kainic acid lesions on performance of place and cue tasks, Behav. Neurosci., 97:873.CrossRefGoogle Scholar
  9. Jarrard, L. E., 1984, Selective hippocampal lesions and behavior: implications for current research and theorizing, in: “The Hippocampus,” R. L. Isaacson and K. Pribram, eds., Plenum Press, New York, in press.Google Scholar
  10. Jarrard, L. E., Okaichi, H., Steward, O., and Goldschmidt, R., 1984, On the role of the hippocampal connections in the performance of place and cue tasks: comparisons with damage to hippocampus, Behav. Neurosci., in press.Google Scholar
  11. Kelley, A. E., and Domesick, V. B., 1982, The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: an anterograde- and retrograde-horseradish peroxidase study, Neurosci., 7:2321.CrossRefGoogle Scholar
  12. Krayniak, P. F., Meibach, R. C., and Siegel, A., 1981, A projection from the entorhinal cortex to the nucleus accumbens in the rat, Brain Res., 209:427.CrossRefGoogle Scholar
  13. O’Keefe, J., 1983, Spatial memory within and without the hippocampal system, in: “Neurobiology of the Hippocampus,” W. Seifert, ed., Academic Press, New York.Google Scholar
  14. Olton, D. S., Becker, J. T., and Handelmann, G. E., 1979, Hippocampus, space, and memory, Behav. Brain Sci., 2:313.CrossRefGoogle Scholar
  15. Orbach, J., Milner, B., and Rasmussen, T., 1960, Learning and retention in monkeys after amygdala-hippocampus resection, Arch. Neurol., 3:230.CrossRefGoogle Scholar
  16. Scoville, W. B., and Milner, B., 1957, Loss of recent memory after bilateral hippocampal lesions, J. Neurol., Neurosurg., Psychiat., 20:11.CrossRefGoogle Scholar
  17. Stein, D. G., Rose, J. J., Graziadec, J., Mishkin, D., and Brink, J., 1969, Central nervous system: recovery of function, Science, 166:528.CrossRefGoogle Scholar
  18. Swanson, L. W., 1979, The hippocampus: new anatomical insights, Trends in Neurosci., 2:9.CrossRefGoogle Scholar
  19. Swanson, L. W., and Cowan, W. M., 1977, An autoradiographic study of the organization of the efferent connections of hippocampal formation in the rat, J. Comp. Neurol., 172:49.CrossRefGoogle Scholar
  20. Vanderwolf, C., and Leung, L. -W. S., 1983, Hippocampal rhythmical slow activity: a brief history and the effects of entorhinal lesions and phencyclidine, in: “Neurobiology of the Hippocampus,” W. Seifert, ed., Academic Press, New York.Google Scholar
  21. Zola-Morgan, S., Squire, L. R., and Mishkin, M., 1982, The neuroanatomy of amnesia: amygdala-hippocampus versus temporal stem, Science, 218:1337.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Leonard E. Jarrard
    • 1
  1. 1.Department of PsychologyWashington and Lee UniversityLexingtonUSA

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