Diagnosis and Treatment of Malignant Lymphomas in the Elderly
The process of aging is associated with structural and functional changes occurring in the living organism and often expressed in gradual deterioration and decline in performance. These impairments result in changes in host resistance and are perhaps the major factors in the emergence of neoplasia in those elderly who have survived the ravages of vascular diseases, accidents, and infection. The hematologic neoplasms are generally diseases of higher incidence with advancing age. These disorders are uncommon under the age of 40; although they do not represent a national health hazard, they are not rare. Malignant lymphomas have an incidence of 82 cases per million. The occurrence of the lymphomas and the ability of the host to deal with them as well as responses to therapy are all modified by advanced age and will be discussed in this chapter.
KeywordsMultiple Myeloma Malignant Lymphoma Mycosis Fungoides Autoimmune Thrombocytopenic Purpura Electron Beam Therapy
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- 7.Greco, R. S., Acheson, R. S., and Foote, F. M., 1974, Hodgkin’s disease in Connecticut from 1935 to 1962: The bimodal incidence curve in the general population and survival in untreated patients, Arch. Intern. Med. 134: 1039–1042.Google Scholar
- 8.Newell, G. R., Cole, S. R., Miettinen, O. S., and MacMahon, B., 1970, Age differences in the histology of Hodgkin’s disease, J. Nat. Cancer, Inst. 45: 311–317.Google Scholar
- 12.DeVita, V. T., Hubbard, S. M., Moxley, J. H., Ill, 1983, The Cure of Hodgkin’s Disease with Drugs, yearbook Medical Publishers, Inc., Chicago, pp. 277–301.Google Scholar
- 15.Jones, S. E., Fuks, Z., Bull, M., Kadin, M. E., Dorfman, R. F., Kaplan, H. S., Rosenberg, S. A., and Kim, H., 1973, Non-Hodgkin’s lymphomas IV. Clinico pathological correlation in 405 cases Cancer 31: 806–823.Google Scholar