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Gene Transfer with Retrovirus Vectors

  • Alan Bernstein
  • Stuart Berger
  • Dennis Huszar
  • John Dick
Part of the Genetic Engineering: Principles and Methods book series (GEPM, volume 7)

Abstract

The ability to introduce new genetic information into animal cells has opened up the possibility of functionally analyzing the regulatory or coding capacity of cloned DNA fragments. This, in turn, has also facilitated the development of techniques for the molecular cloning of eukaryotic genes on the basis of their ability to alter the phenotype of the recipient cell. Thus, there is now considerable interest in the development of improved methods of gene transfer, applicable to a wide range of cell types both in cell culture and the intact animal.

Keywords

Helper Virus Polyoma Virus Severe Combine Immunodeficiency Disease Transcriptional Orientation Replication Competent Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Alan Bernstein
    • 1
    • 2
  • Stuart Berger
    • 1
    • 2
  • Dennis Huszar
    • 1
    • 2
  • John Dick
    • 1
    • 2
  1. 1.Division of Biological ResearchOntario Cancer InstituteTorontoCanada
  2. 2.Department of Medical BiophysicsUniversity of TorontoTorontoCanada

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