Mutation in Single-Cell Systems Induced by Low-Level Mutagen Exposure

  • Howard L. Liber
  • Susan L. Danheiser
  • William G. Thilly
Part of the Basic Life Sciences book series


A principal question currently facing toxicologists and radio-biologists concerns how measurements can be made of mutations induced by low levels of chemicals or radiation. In this paper, we focus on measurements in single cell systems. We consider that cellular exposure to mutagens occurs via four modes.


Dose Rate Repair System Mutation Induce High Dose Rate Mutation Assay 


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Howard L. Liber
    • 1
  • Susan L. Danheiser
    • 1
  • William G. Thilly
    • 1
  1. 1.Genetic Toxicology GroupMassachusetts Institute of TechnologyCambridgeUSA

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