Production of Rat × Mouse Hybridomas for the Study of the Nicotinic Acetylcholine Receptor

  • Susan M. Hochschwender
  • Lorene K. Langeberg
  • Douglas W. Schneider
  • Jon M. Lindstrom


In this chapter we will discuss methods used in our laboratory for the production of monoclonal antibodies (MAbs) to acetylcholine receptors (AChRs) and their use in obtaining information on AChR structure, function, and synthesis, the autoimmune response to AChR, and the identification of putative AChRs in neurons. Space limitations preclude extensive discussion and referencing of work done in other laboratories in this field.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Susan M. Hochschwender
    • 1
  • Lorene K. Langeberg
    • 1
  • Douglas W. Schneider
    • 1
  • Jon M. Lindstrom
    • 1
  1. 1.Recepter Biology LaboratorySalk InstituteSan DiegoUSA

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