GABA and Glycine: Ion Channel Mechanisms

  • Jeffery L. Barker


It is now evident that the naturally occurring neutral amino acids γ-aminobutyric acid (GABA) and glycine are present in many, if not all, nervous systems and that these substances mediate specific types of intercellular communication. Although their actions in the mammalian central nervous system (CNS) have been studied for 30 years, it is only recently that some understanding of the membrane mechanisms underlying the transmitter actions of these substances has been achieved. Chapter 2 reviews the cellular physiology of GABA and glycine based upon studies in vivo, in acutely prepared slices of CNS tissue, and in peripheral ganglia.


Current Response Neutral Amino Acid Membrane Conductance Spinal Neuron Central Nervous System Tissue 
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© Plenum Press, New York 1985

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  • Jeffery L. Barker

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