Governmental Responsibilities and Genetic Disease

  • Seymour Lederberg


Governmental responsibility for dealing with genetic disorders is an old story that has expressed itself primarily through the knife, the law, and the purse. These past approaches are identified with the transmission of genetic handicaps, their detection by screening programs, and their understanding and treatment. In order to ask what government responsibilities should be, it may be instructive to review the contributions of these past efforts.


Cystic Fibrosis Governmental Responsibility Recessive Genetic Disorder Heterozygote Carrier Retarded Parent 
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  1. 1.
    O’Hara, J. B., and Sanks, T. H., Eugenic sterilization, Georgetown Law J. 45:20 (1956).Google Scholar
  2. 2.
    Haller, M. H., Eugenics ,Rutgers University Press, New Brunswick, NJ (1963).Google Scholar
  3. 3.
    Robitscher, J., Eugenic Sterilization ,Charles C Thomas, Springfield, IL (1973).Google Scholar
  4. 4.
    Ludmerer, K. M., Genetics and American Society ,Johns Hopkins University Press, Baltimore (1972).Google Scholar
  5. 5.
    Buckv. Bell ,143 Va. 310(1925).Google Scholar
  6. 6.
    Buck V. Bell ,274 U.S. 200 (1927).Google Scholar
  7. 7.
    Skinner V. Oklahoma ,316 U.S. 535 (1942).Google Scholar
  8. 8.
    Roe V. Wade ,410 U.S. 113 (1973).Google Scholar
  9. 9.
    See 8 supra and Doe V. Bolton ,410 U.S. 179 at 215.Google Scholar
  10. 10.
    Conneally, P. M., Merritt, A. D., and Yu, P-L., Cystic fibrosis: Population genetics, Texas Reports on Biology and Medicine 31:639–50 (1973).PubMedGoogle Scholar
  11. 11.
    Reed, E. W., and Reed, S. C, Mental Retardation: A Family Study ,W. B. Saunders, Philadelphia (1965), 56.Google Scholar
  12. 12.
    State Laws and Regulations on Genetic Disorders, July 1980 ,U.S. Dept. Health and Human Services, DHHS Publication No. (HSA) 81–5243 (1981).Google Scholar
  13. 13.
    Furman, B., A Profile of the United States Public Health Service 1798–1948 ,U.S. Dept. of Health, Education and Welfare, DHEW Publication No. (NIH) 73–369 (1973).Google Scholar
  14. 14.
    Chang, J. C, and Kan, Y. W. A sensitive new prenatal test for sickle cell anemia, N. Eng. J. Med. 307:30–2 (1982).CrossRefGoogle Scholar
  15. 15.
    Orkin, S. H., et al. ,The molecular basis of a-thalassemias: Frequent occurrence of dysfunctional a loci among non-Asians with Hb H disease, Cell 17:33–42 (1979).Google Scholar
  16. 16.
    Gusella, J. F., et al. ,A polymorphic DNA marker genetically linked to Huntington’s disease, Nature 306:234–8 (1983).PubMedCrossRefGoogle Scholar
  17. 17.
    Mann, R., Mulligan, R. C., and Baltimore, D., Construction of a retrovirus packaging mutant and its use to produce helper free defective retrovirus, Cell 33:153–9 (1983).PubMedCrossRefGoogle Scholar

Copyright information

© Aubrey Milunsky and George J. Annas 1985

Authors and Affiliations

  • Seymour Lederberg
    • 1
  1. 1.Brown UniversityProvidenceUSA

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