Abstract
Unlike B lymphocytes which have a single major function, the secretion of antibody, T lymphocytes mediate a variety of immunologic and nonimmunologic functions. Human T cells can be divided into several distinct cell types or subsets, which interact through cell surface molecules with one another, monocytes, and B cells to generate and regulate immunity. In addition, many T-cell functions appear to be mediated wholly or in part by soluble immunoregulatory factors, or lymphokines, at least as numerous as the subsets from which they are derived. Thus, an understanding of immune function in man depends on a thorough knowledge of the structure and actions both of T-cell surface molecules and T-cell-derived lymphokines.
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Coutre, S., Foung, S.K.H., Engleman, E.G. (1985). Human T-Lymphocyte Subsets and T-T Hybridomas. In: Engleman, E.G., Foung, S.K.H., Larrick, J.W., Raubitschek, A.A. (eds) Human Hybridomas and Monoclonal Antibodies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4949-5_18
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DOI: https://doi.org/10.1007/978-1-4684-4949-5_18
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