Abstract
There is considerable interest in the lipoxygenation of mitochondrial membranes because of the inhibitory influence this process can have on mitochondrial activities such as oxidative phosphorylation (Vladimirov et al., 1980). In addition, mitochondrial lipid peroxidation has been associated with several important pathological conditions. These include hypoxia and postischemic reperfusion (Hillered and Ernster, 1983), aging (Nohl et al., 1978), and the cytotoxicity of many chemicals as well as UV or ionizing radiation (Vladimirov et ai., 1980).
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References
Boches, F. S., and Goldberg, A. L., 1982, Role for the adenosine triphosphate-dependent proteolytic pathway in reticulocyte maturation, Science 215:978–980.
Bryant, R.W., Bailey, J.M., Schewe, T., and Rapoport, S.M., 1982, Positional specificity of a reticulocyte lipoxygenase: Conversion of arachidonic acid to 15S-hydroperoxy-eicosatetraenoic acid, J. Biol. Chem. 257:6050–6055.
Chappell, J.B., and Crofts, A.R., 1965, Calcium accumulation and volume changes of isolated mitochondria, Biochem. J. 95:378–392.
Fiskum, G., 1984, Physiological aspects of mitochondrial calcium transport, in: Metal Ions in Biological Systems, Vol. 17: Calcium and Its Role in Biology (H. Sigel, ed.), Marcel Dekker, New York, pp. 187–214.
Fiskum, G., Bryant, R.W., Pease, A., and Bailey, J.M., 1983, Influence of reticulocyte lipoxygenase and 15-HETE on mitochondrial energy coupling, Fed. Proc. 42:2251.
Halangk, W., Schewe, T., Hiebsch, C, and Rapoport, S.M., 1977, Some properties of the lipoxygenase from rabbits reticulocytes, Acta Biol. Med. Germ. 36:405–110.
Hillered, L., and Ernster, L., 1983, Respiratory activity of isolated rat brain mitochondria following in vitro exposure to oxygen radicals, J. Cereb. Blood Flow Metab. 3:207–214.
Hughes, H., Smith, C.V., Horning, E.C, and Mitchell, J.R., 1983, High performance liquid chromatography and gas chromatography-mass spectrometry determination of specific lipid per-oxidation products in vivo, Anal. Biochem. 130:431–436.
Krause, W., and Halangk, W., 1977, Relationship between conformational state and susceptibility to reticulocyte lipoxygenase of rat liver mitochondria, Acta Biol. Med. Germ. 36:381–387.
Lawrence, R. A., and Burk, R. F., 1976, Glutathione peroxidase activity in selenium-deficient rat liver, Biochem. Biophys. Res. Commun. 71:952–958.
Muller, M., Dubiel, W., Rathmann, J., and Rapoport, S. M., 1980, Determination and characteristics of energy-dependent proteolysis in rabbit reticulocytes, Eur. J. Biochem. 109:405–410.
Nohl, H., Breuninger, V., and Hegner, D., 1978, Influence of mitochondrial radical formation on energy-linked respiration, Eur. J. Biochem. 90:385–390.
Rapoport, S. M., Schewe, T., Wiesner, R., Halangk, W., Ludwig, P., Janicke-Hohne, M., Tannert, C, Hiebsch, C, and Klatt, D., 1979, The lipoxygenase of reticulocytes: Purification, characterization and biological dynamics of the lipoxygenase; its identity with the respiratory inhibitors of the reticulocyte, Eur. J. Biochem. 96:545–561.
Scrapa, A, and Lindsay, J. G., 1972, Maintenance of energy-linked functions in rat liver mitochondria aged in the presence of nupercaine, Eur. J. Biochem. 27:401–407.
Schewe, T., Halangk, W., Hiebsch, C, and Rapoport, S.M., 1975, A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria, FEBS Lett. 60:149–152.
Schewe, T., Halangk, W., Hiebsch, C, and Rapoport, S., 1977, Degradation of mitochondria by cytosolic factors in reticulocytes, Acta Biol. Med. Germ. 36:363–372.
Schnaitman, C.A., and Greenawalt, J.W., 1968, Enzymatic properties of the inner and outer membranes of rat liver mitochondria, J. Cell Biol. 38:158–175.
Sies, H., and Moss, K.M., 1978, A role of mitochondrial glutathione peroxidase in modulating mitochondrial oxidations in liver, Eur. J. Biochem. 84:377–383.
Speiser, S., and Etlinger, J.D., 1982, Loss of ATP-dependent proteolysis with maturation of reticulocytes and erythrocytes, J. Biol. Chem. 257:14122–14127.
Thiele, B.J., Belkner, J., Andree H., Rapoport, T.A., and Rapoport, S.M., 1979, Synthesis of non-globin proteins in rabbit-erythroid cells: Synthesis of a lipoxygenase in reticulocytes, Eur. J. Biochem. 96:563–569.
Vladimirov, Y.A., Olenev, V.I., Suslova, T.B., and Cheremisina, Z.P., 1980, Lipid peroxidation in mitochondrial membrane, Adv. Lipid Res. 17:173–249.
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Fiskum, G., Bryant, R.W., Low, CE., Pease, A., Bailey, J.M. (1985). Lipoxygenation of Mitochondrial Membranes by Reticulocyte Lipoxygenase. In: Bailey, J.M. (eds) Prostaglandins, Leukotrienes, and Lipoxins. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4946-4_9
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