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Differential Effects of Leukotriene B4 and Its Analogues on Suppressor and Helper Cell Function

  • Marek Rola-Pleszczynski
  • Lyne Gagnon
  • Victor Radoux
  • Claudine Pouliot
  • E. J. Corey
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

Recent studies have demonstrated that leukotrienes (LTs), in addition to their myotropic properties, also strongly affect several leukocyte functions. For instance, LTB4 was shown to stimulate neutrophil aggregation (Bass et al., 1981), chemokinesis (Ford-Hutchinson et al., 1980; Palmer et al., 1980), chemotaxis (Palmer et al., 1980), degranulation (Showell et al., 1982a), hexose transport (Bass et al., 1981), and cation fluxes (Molski et al., 1981).

Keywords

Helper Cell Suppressor Cell Hexose Transport Lipoxygenase Product Neutrophil Degranulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Marek Rola-Pleszczynski
    • 1
  • Lyne Gagnon
    • 1
  • Victor Radoux
    • 1
  • Claudine Pouliot
    • 1
  • E. J. Corey
    • 2
  1. 1.Immunology Division, Faculty of MedicineUniversity of SherbrookeSherbrookeCanada
  2. 2.Department of ChemistryHarvard UniversityCambridgeUSA

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