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The Differentiated Contractile Effects of Prostaglandins on the Various Segments of the Pregnant Human Uterus

  • B. Lindblom
  • M. Wikland
  • N. Wiqvist
  • I. Bryman
  • A. Norström
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

It is by now well established that prostanoids play a central role in the regulation of myometrial activity and thereby in the physiological control of human parturition (Liggins, 1979). Evidence for this concept is that exogenous PGs are effective for induction of labor (Karim et al., 1969; Thiery and Amy, 1975) and that inhibitors of PG biosynthesis are able both to delay spontaneous labor (Lewis and Schulman, 1973) and to inhibit preterm labor (Zuckerman et al., 1974; Wiqvist, 1979). To date, though, no evidence has emerged showing an increased formation of PG compounds prior to the spontaneous onset of parturition.

Keywords

Lower Segment Lower Uterine Segment Spontaneous Labor Human Parturition Human Myometrium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • B. Lindblom
    • 1
  • M. Wikland
    • 1
  • N. Wiqvist
    • 1
  • I. Bryman
    • 1
  • A. Norström
    • 1
  1. 1.Department of Obstetrics and GynecologyUniversity of GöteborgGöteborgSweden

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