Prostaglandins in Human Seminal Fluid and Its Relation to Fertility
Human seminal fluid contains a number of prostaglandins (PGs) in large amounts. The first identified compounds were PGE1, PGE2, PGE3, PGF1, and PGF2α (Samuelsson, 1963). More recently, 19-hydroxy-PGE1, 19-hydroxy-PGE2, 19-hy-droxy-PGF1α, and 19-hydroxy-PGF2α have been identified. The 8ß-isomers of these compounds are also present (Taylor, 1979; Taylor and Kelly, 1974, 1975). Although 50 years have now elapsed since von Euler (1936) first identified a new type of compound in human semen, which he named prostaglandin, the physio-logical function of the PGs in semen is still far from clarified. In this chapter, different possibilities that we have started to evaluate during the last years are discussed.
KeywordsSeminal Vesicle Sperm Motility Human Semen Sperm Density Sperm Characteristic
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