Protein A Immunoadsorption/Immunoactivation: A Critical Review

  • Mehmet F. Fer
  • Robert K. Oldham
Part of the Contemporary Topics in Immunobiology book series (CTI, volume 15)


Over the past several years, reports have been published describing antitumor effects of autologous plasma after contact with protein A or bacterial products containing protein A (Bansal et al., 1978; Bensinger et al., 1981; Holohan et al., 1982; Jones et al., 1980; Terman et al., 1980, 1981). Although the efficacy of these manipulations, the best reagents to use, and the mechanism of action are all unclear, considerable enthusiasm regarding the effects of protein A has been generated. This chapter will review the available information on protein A-related plasma immunoadsorption/immunoactivation studies for cancer therapy and to summarize current thoughts and controversies.


Thrombotic Thrombocytopenic Purpura Antitumor Response Circulate Immune Complex Autologous Plasma Plasma Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Mehmet F. Fer
    • 1
  • Robert K. Oldham
    • 2
  1. 1.Section of Hematology/OncologyUniversity of Kentucky Medical CenterLexingtonUSA
  2. 2.Biological Therapy InstituteFranklinUSA

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