Physiology and Pathophysiology of Human Neutrophils
Circulating blood phagocytes, including neutrophils (polymorphonuclear leukocytes [PMN]) as well as monocytes, can recognize, ingest, kill, and, to a certain extent, digest microbes. These blood cells, therefore, are of crucial importance in host defense against invading microorganisms. Disorders in this line of defense are accompanied by serious, recurrent bacterial and fungal infections. In the last decade, a number of these often inherited disorders have been classified and their origin recognized.
KeywordsChronic Granulomatous Disease Cytoplasmic Granule Microtubule Assembly Specific Granule Phagocytic Vacuole
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