Lymphocyte Migration Studies in Man

  • John Wagstaff
Part of the NATO ASI Series book series (NSSA, volume 88)


Over 200 years ago William Hewson (1) shrewdly observed that,

“Vast numbers of central particles (Lymphocytes) made by the thymus and lymphatic glands, are poured into the blood vessels through the thoracic duct and if we examine the blood attentively we can see them floating in it. Nature surely would not make so infinitely many particles to answer no purpose! What then becomes of these particles after they are mixed with the circulating blood are they immediately destroyed? No. They are we believe, carried with the blood to the spleen, not that the spleen has any elective attraction over them but that being equally and uniformly diffused through the general mass of blood, a due proportion is received by the spleen with its arterial blood, and that when arrived there, the spleen has the power of separating them from the other parts of the blood...”.


Synovial Fluid Chronic Lymphocytic Leukemia Peripheral Blood Lymphocyte Human Lymphocyte Chronic Lymphocytic Leukemia Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • John Wagstaff
    • 1
  1. 1.Cancer Research Campaign Department Medical OncologyChristie Hospital and Holt Radium InstituteManchesterEngland

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