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Radiolabeled Cellular Blood Elements pp 265–284Cite as

Present Trends and Future Directions in “Leukocyte Labeling”

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Part of the book series: NATO ASI Series ((NSSA,volume 88))

Abstract

Imaging with In-111-labeled leukocytes has become an established clinical method for the detection of focal inflammatory lesions in many medical centers but has been rejected by others because of the technical complexities of the labeling procedure. Gaining knowledge of the in vivo migratory pattern of the different leukocyte populations and subtypes in health and disease remains an important goal(1), particularly in the field of immunology. Techniques for examining the in vivo distribution of lymphocytes, monocytes and the eosinophils are still under development, and differences in migratory patterns of mononuclear subtypes remain to be explored. This paper attempts to summarize recent progress in the techniques of harvesting and labeling leukocytes and suggests possible directions for future research.

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Authors and Affiliations

  1. Divisions of Radiological Sciences and Nuclear Medicine Department of Radiology, Upstate Medical Center, S.U.N.Y., Syracuse, New York, 13210, USA

    John G. McAfee, Gopal Subramanian & George Gagne

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  1. John G. McAfee
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  2. Gopal Subramanian
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  3. George Gagne
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Editors and Affiliations

  1. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

    M. L. Thakur (Editor, and the ASI Director) (Editor, and the ASI Director)

  2. Yale University School of Medicine, New Haven, Connecticut, USA

    M. D. Ezikowitz

  3. University of Amsterdam, Amsterdam, The Netherlands

    M. R. Hardeman

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© 1985 Plenum Press, New York

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McAfee, J.G., Subramanian, G., Gagne, G. (1985). Present Trends and Future Directions in “Leukocyte Labeling”. In: Thakur, M.L., Ezikowitz, M.D., Hardeman, M.R. (eds) Radiolabeled Cellular Blood Elements. NATO ASI Series, vol 88. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4922-8_13

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