Genetic Analysis of Duchenne Dystrophy
We have heard many interesting presentations on the physiology and genetic structure of muscle related proteins. The examples have ranged from dystrophic muscle cells in culture to very specific analysis of both actin and myosin genes. I would like to present some of the genetic analyses of the human X chromosome being pursued in the Genetics Division at Children’s Hospital in Boston. My presentation will concentrate mainly on our efforts to develop diagnostically useful restriction fragment length polymorphisms (RFLPs) (579) for the human X-linked muscular dystrophies. I will close my presentation with some initial attempts at “walking” (580) in specific X chromosomal regions.
KeywordsDUCHENNE Dystrophy Duchenne Muscular Dystrophy Becker Dystrophy Myosin Gene Genetic Division
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