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Muscle Gene Expression in Heterokaryons

  • Helen M. Blau
  • Choy-Pik Chiu
  • Grace K. Pavlath
  • Cecelia Webster
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 182)

Abstract

One approach to the study of how gene regulation occurs during muscle differentiation and development is to put a non-muscle cell into an environment where it is reprogrammed to synthesize muscle proteins, which it would never normally express. One way to do this is to fuse two cells together. In this talk I will show you how this kind of fusion system can be used to ascertain the requirements for gene expression and to address certain questions about the determination and differentiation.

Keywords

Myosin Light Chain Human Muscle Synthesize Muscle Protein Cytosine Arabinoside Mouse Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Helen M. Blau
    • 1
  • Choy-Pik Chiu
    • 1
  • Grace K. Pavlath
    • 1
  • Cecelia Webster
    • 1
  1. 1.Department of PharmacologyStanford University School of MedicineStanfordUSA

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