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Synthesis and Accumulation of Myosin Isozymes in Tissue Culture

  • Robert G. Whalen
  • Lawrence B. Bugaisky
  • Gillian S. Butler-Browne
  • Marion S. Ecob
  • Christian Pinset
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 182)

Abstract

Several questions can be asked concerning the synthesis and accumulation of myosin subunits and their isoforms in muscle cells grown in tissue culture. Do any of the transitions which characterize muscle development in vivo take place in tissue culture? Do myoblasts taken from animals of different ages, or from different muscle types synthesize the same myosin isozymes? Is morphological maturity of a muscle fiber in culture paralleled by accumulation of adult muscle myosins? We have examined each of these questions in three different tissue culture situations.

Keywords

Satellite Cell Organotypic Culture Tissue Culture System Myotube Formation Fast Myosin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Robert G. Whalen
    • 1
  • Lawrence B. Bugaisky
    • 1
  • Gillian S. Butler-Browne
    • 1
  • Marion S. Ecob
    • 2
  • Christian Pinset
    • 1
  1. 1.Departement de Biologie MoleculaireInstitute PasteurNewcastle upon TyneGreat Britain
  2. 2.Muscular Dystrophy LaboratoriesNew Castle General HospitalNewcastle upon TyneGreat Britain

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