Abstract
Recently-introduced anti-ulcer agents such as H2 receptor antagonist and selective muscarinic receptor antagonist have yielded a good therapeutic result for intractable peptic ulcer. These drugs have a powerful anti-secretory effect. Possible additional effects of these drugs, however, have also been discussed (1–3). Prostaglandins (PGs) and their analogs have been reported to show potent gastric anti-secretory action (4) and inhibit the experimental ulceration independently of any anti-secretory action (5). It is suggested that PGs have a “cytoprotective effect” on the gastric mucosa (6).
On leave of absence from Department of Pathophysiology, Chinese Medical College, Shen Yang, China
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© 1984 Plenum Press, New York
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Sato, N., Quan, L.H., Kawano, S., Kamada, T., Abe, H. (1984). Effect of H2 Receptor- and Muscarine Receptor Antagonists and Prostaglandin E1 Analog on the Gastric Mucosal Hemodynamics and Oxygen Sufficiency in Rats. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_75
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DOI: https://doi.org/10.1007/978-1-4684-4895-5_75
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