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Balance between O2 Availability and V̇O2 in Rest-Work Transition as Measured by Myoglobin Saturation in Subcellular Volumes

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Oxygen Transport to Tissue—VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 180))

Abstract

The rate of O2 consumption (V̇O2) may increase 100-fold between rest and steady work in red skeletal muscles (1,2). Does hyperemia supply O2 at a rate which keeps pace with this massive increase in O2 demand, or is an O2 debt incurred? Does exercise hyperemia depend on O2 lack (3), a redox signal (4), or cytosolic energy charge (5)? To answer these questions we related the time course of exercise hyperemia to myoglobin (Mb) saturation in subcellular volumes (6,7). ATP, creatine phosphate (PCr), lactate (LA), and pyruvate (Pyr) concentrations were co-variates.

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References

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Authors and Affiliations

  1. School of Medicine and Dentistry, The University of Rochester, 601 Elmwood Avenue, Rochester, New York, 14642, USA

    Carl R. Honig, Thomas E. J. Gayeski & Richard J. Connett

Authors
  1. Carl R. Honig
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  2. Thomas E. J. Gayeski
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  3. Richard J. Connett
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Editor information

Editors and Affiliations

  1. California Polytechnic State University, San Luis Obispo, California, USA

    Duane Bruley

  2. Western Tumor Medical Group, Van Nuys, California, USA

    Haim I. Bicher

  3. Louisiana Tech University, Ruston, Louisiana, USA

    Daniel Reneau

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© 1984 Plenum Press, New York

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Honig, C.R., Gayeski, T.E.J., Connett, R.J. (1984). Balance between O2 Availability and V̇O2 in Rest-Work Transition as Measured by Myoglobin Saturation in Subcellular Volumes. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_63

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  • DOI: https://doi.org/10.1007/978-1-4684-4895-5_63

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4897-9

  • Online ISBN: 978-1-4684-4895-5

  • eBook Packages: Springer Book Archive

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