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Computer Controlled Blood Pressure Changes Required for Steady State Oxygen Control of Partial Ischemia in the Rat Brain Cortex

  • K. A. Conger
  • H. P. Moraes
  • E. R. Strong
  • K. Hino
  • L. Briggs
  • J. H. Garcia
  • J. H. HalseyJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 180)

Abstract

We have been interested in determining the duration and severity of ischemia necessary to injure cerebral cortical neurons. In preliminary experiments in the monkey, we had noticed that the earliest histological change is vacuolation of dendrites followed by progressive vacuolation in the cell body.1

Keywords

Systemic Arterial Pressure Left Vertebral Artery Cerebral Cortical Neuron Carotid Artery Ligation Bilateral Vertebral Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. 1.
    J.H. Garcia, H.L. Mitchem, L. Briggs, R. Morawetz, A.G. Hudetz, J.B. Hazelrig, J. Halsey, K. Conger. Transient focal ischemia in subhuman primates. J. Neuropath. Exper. Neurol. 42:44–60 (1983).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • K. A. Conger
    • 1
  • H. P. Moraes
    • 1
  • E. R. Strong
    • 1
  • K. Hino
    • 1
  • L. Briggs
    • 1
  • J. H. Garcia
    • 1
  • J. H. HalseyJr.
    • 1
  1. 1.University of Alabama Medical CenterUniversity StationBirminghamUSA

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