Computer Controlled Blood Pressure Changes Required for Steady State Oxygen Control of Partial Ischemia in the Rat Brain Cortex

  • K. A. Conger
  • H. P. Moraes
  • E. R. Strong
  • K. Hino
  • L. Briggs
  • J. H. Garcia
  • J. H. HalseyJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 180)

Abstract

We have been interested in determining the duration and severity of ischemia necessary to injure cerebral cortical neurons. In preliminary experiments in the monkey, we had noticed that the earliest histological change is vacuolation of dendrites followed by progressive vacuolation in the cell body.1

Keywords

Ischemia Platinum Neurol 

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Reference

  1. 1.
    J.H. Garcia, H.L. Mitchem, L. Briggs, R. Morawetz, A.G. Hudetz, J.B. Hazelrig, J. Halsey, K. Conger. Transient focal ischemia in subhuman primates. J. Neuropath. Exper. Neurol. 42:44–60 (1983).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • K. A. Conger
    • 1
  • H. P. Moraes
    • 1
  • E. R. Strong
    • 1
  • K. Hino
    • 1
  • L. Briggs
    • 1
  • J. H. Garcia
    • 1
  • J. H. HalseyJr.
    • 1
  1. 1.University of Alabama Medical CenterUniversity StationBirminghamUSA

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