Distribution of Cerebrocortical Microflow in Normo- and Hypertensive Rats
It has been demonstrated by Choki et al. (1977) that rCBF measured by C antipyrine autoradiography was significantly lower after 2 hours of bilateral carotid ligation in the group of spontaneously hypertensive rats than in that of normotensive animals. The hypertensive brain has been found weak as compared to the normotensive in the circulatory adaptation to transient ischemic episodes (Halsey et al., 1980). In search for an explanation for the impaired circulatory adaptation of the hypertensive brain in ischemia, we have studied the intraparenchymal distribution of blood content — as an idex of vascular caliber — and blood flow through cerebrocortical microareas of normotensive (NTR) and spontaneously hypertensive (SHR) rats under normal conditions.
KeywordsBrain Cortex Reflectance Image Hypertensive Group Blood Content Normotensive Group
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