Perfused Canine Brain: Metabolism and Blood-Brain Transport During Altered Metabolic States

  • Lester R. Drewes
  • Ashok K. Singh
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 180)


Each organ system of the mammalian anatomy is recognized as performing a unique or specific function in the overall biological activity of the organism. Every organ, in turn, also consists of several cell types, each with often divergent and unique properties that collectively carry out the functions of the particular organ. One approach to investigate the biochemical and physiological properties is to isolate and perfuse the organ with an extracorporeal system.


Octanoic Acid Cerebral Metabolism Cerebral Metabolic Rate Adenylate Energy Charge Local Cerebral Blood Flow 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Lester R. Drewes
    • 1
  • Ashok K. Singh
    • 1
  1. 1.Department of Biochemistry, School of MedicineUniversity of Minnesota, DuluthDuluthUSA

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