Immunology and Embryogenesis: The Chromosomal Editing Hypothesis

  • William J. Dreyer
  • Janet M. Roman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 181)


Time lapse movies of migrating T-cells remind us very much of nerve growth cones. Both sense the environment with ameboid-like processes as they seek their respective targets. The genetic, molecular and cellular basis for the production of the specificity on B-cells and T-cells is understood to an extraordinary degree at this point in history. On the other hand, the specificity found on cells in the developing nervous system is only understood at the level of descriptive biology.


Nuclear Transplantation Epigenetic Factor Antibody Molecule Editing Event Antibody Diversity 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • William J. Dreyer
    • 1
  • Janet M. Roman
    • 1
  1. 1.Division of BiologyCalifornia Institute of TechnologyPasadenaUSA

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