Abstract
Isozyme patterns of experimental both solid and ascites rat hepatomas have been extensively investigated in recent years. For many enzymes, such as hexokinase (Sato and Sugimura, 1973), pyruvate kinase (Farina et al., 1974), alcohol dehydrogenase (Cederbaum and Rubin, 1976), glycogen phosphorilase (Sato et al., 1976), acid and alkaline phosphatases (Emmelot and Bos,1969; Kaneko et al., 1972), malate dehydrogenase (Otani and Morris, 1971), aspartate and alanine aminotransferase (Otani and Morris, 1971), tyrosine aminotransferase (Aviram and Hershko, 1977), S-adenosylmethionine synthetase (Liau et al., 1979; Tsukada and Okada, 1980) evidence has been given that the disappearance of some enzymatic components that are typical of the normal adult rat liver and appearance of new, frequently foetal-type isozymes generally correspond to the degree of dedifferentiation and to the growth rate of the tumor.
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© 1984 Plenum Press, New York
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Gazzaniga, P.P. (1984). Heterogeneity of Extramitochondrial Forms of Aspartate Aminotransferase and Malate Dehydrogenase in Yoshida Ascites Hepatoma Cells. In: Aaronson, S.A., Frati, L., Verna, R. (eds) Genetic and Phenotypic Markers of Tumors. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4856-6_9
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DOI: https://doi.org/10.1007/978-1-4684-4856-6_9
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