Intestinal Absorption and Secretion of Fluid and Electrolytes
Knowledge of the mechanisms that regulate small and large intestinal fluid and electrolyte movement has greatly expanded during the past decade. Detailed examination of individual transport processes present in the intestinal epithelia has provided insight into the control of both absorptive and secretory events. Studies of man have emphasized that the fluid load to the intestine is considerably greater than that previously appreciated and that diarrhea is almost always secondary to changes in fluid and electrolyte movement. Finally, the heterogeneity of various segments of the intestine has become increasingly evident and must be appreciated in the development of models to explain the overall control of fluid and electrolyte movement in health and disease.
KeywordsApical Membrane Sodium Absorption Fluid Load Active Potassium Absorptive Process
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- 1.H.J. Binder, Absorption and secretion of water and electrolytes by small and large intestine, "Gastrointestinal Diseases", M.H. Sleisenger and J.S. Fordtran, eds., W.B. Saunders Co., Philadelphia, (1983).Google Scholar
- 2.P.S. Aronson., Identifying secondary active solute transport in epithelia. Am. J. Physiol., 9: Fl (1981).Google Scholar
- 5.R.F. Gregor and E. Schlatter, Coupled transport of 2 CI-, 1 Na+ and 1 K+ at the luminal membrane of the rabbit cortical thick ascending limb of Henle’s loop (CTAL), Proc. Am. Soc. Nephrol., 14: 147 (1981).Google Scholar
- 9.M.A. Balaa and D.W. Powell, Prostaglandin synthesis by isolated rabbit small intestinal enterocytes. Gastroenterology, 84: 1098 Abstract (1983).Google Scholar
- 11.E.S. Foster, J.P. Hayslett, and H.J. Binder, Regulation of active potassium absorption and secretion in rat distal colon. Gastroenterology, 84: 1157 Abstract (1983).Google Scholar