Histopathological Findings Relating to Disordered Motility and Secretion
Patterns of motility and secretion may be altered in several ways. For example, disease processes (congenital or acquired) may interfere with either neural or endocrine control mechanisms or with the musculature or connective tissue of the gut wall. The function of a particular cell is also dependent on the expression of genotype and this will be influenced by interactions between the cell and its environment. Some consideration will first be given to the ways in which motility and secretory control mechanisms become deranged, emphasizing morphological findings. Secondly, examples of altered secretory activity associated with disorders of differentiation will be presented.
KeywordsIntestinal Metaplasia Diverticular Disease Myenteric Plexus Pyloric Stenosis Secretory Component
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- Eastwood, M.A., Watters, D.A.K., and Smith, A.N., 1982, Diverticular disease - Is it a motility disorder? in: “ Clinics in Gastroenterology vol 11/Number 3, Motility and its disturbances,” A.M. Connell, ed., Saunder Co. Ltd, London Philadelphia Toronto.Google Scholar
- Howard, E.R., Garrett, J.R., and Kidd, A., 1982, Congenital neuronal disorders of the hind-gut: the value of ano-rectal biopsies, Scand. J. Gastroenterol., (suppl) 71:151.Google Scholar
- Jass, J.R., Filipe, M.I., Abbas, S., Falcon, C.A.J., Wilson, Y., and Lovell, D., 1982, Altered expression of carcinoembryonic antigen and sialomucin in metaplastic polyps of the colorectum, IRCS Med. Sci., 10:678.Google Scholar
- Lake, B.D., 1983, Hirschsprung’s disease, “Histo chemistry in Pathology,” M.I. Filipe and B.D. Lake, eds., Churchill Livingstone, Edinburgh London, New York.Google Scholar
- Morson, B.C., and Dawson, I.M.P., 1979, “Gastrointestinal Pathology,” Blackwell Scientific Publications, Oxford.Google Scholar
- Painter, N.S., 1975, in:“Diverticular disease of the colon,” William Heineman Medical Books, London.Google Scholar
- Sipponen, P., Seppala, K., Varis, K., Hjelt, L., Ihamaki, T-, Kekki, M., and Siurala, M., 1980, Intestinal metaplasia with colonic type sulphomucins in the gastric mucosa; its association with gastric carcinoma. Acta. Path. Microbiol. Scand., 88:217.Google Scholar
- Smith, B., 1970, The neurological lesion of achalasia of the cardia. Girt, 11:388.Google Scholar
- Solcia, E., Capella, C., Buffa, R., Usellini, L., Fiocca, R., Frigerio, B., Tenti, P., and Sessa, F., 1981, The diffuse endocrine-paracrine system of the gut in health and disease: ultrastructural features, Scand. J. Gastroenterol., (Suppl) 70:25.Google Scholar
- Snape, W.J., 1982, Pseudo-obstruction and otherm obstructive disorders, in: “Clinics in Gastroenterology vol 11/Number 3, Motility and its disturbances,” A.M. Connell, ed., W.B. Saunders and Co. Ltd., London Philadelphia Toronto.Google Scholar
- Vantrappen, G., and Hellemans, J., 1982, Motor disorders of the oesophagus, in: “Topics in Gastroenterology vol 10,” D. P. Jewell and W.S. Selby eds., Blackwell Scientific Publications, Oxford.Google Scholar