Arrangement and Rearrangement of Bacterial Genomes

  • Monica Riley
Part of the Monographs in Evolutionary Biology book series (MEBI)


In the preceding chapters, experimental systems have been described in which mechanisms of evolution of bacterial genes by point mutation have been fruitfully studied. In this chapter, the focus will be on rearrangements, some on a small scale, occurring within genes, and others on a large scale, causing gross chromosomal rearrangements of the whole bacterial genome. On the whole, less is known about the molecular events of chromosome rearrangement than is known about point mutations, and even less is known about the pressures for stabilization and destabilization of genome structure. Occurrences of large-scale changes in the genome have no doubt played important roles in evolution. In this chapter progress in understanding the molecular mechanisms of rearrangement and the mechanisms of resistance to change will be summarized with emphasis on experiments that have been done with Escherichia coli and its close relatives.


Gene Pair Bacterial Genome Tandem Duplication Inverted Repeat Sequence Illegitimate Recombination 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Monica Riley
    • 1
  1. 1.Department of BiochemistryState University of New York at Stony BrookStony BrookUSA

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