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Reproduction pp 77–98Cite as

Sexual Behavior Differentiation

Effects of Prenatal Manipulations in Rats

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Part of the book series: Handbook of Behavioral Neurobiology ((HBNE,volume 7))

Abstract

The first concrete demonstration that fetal testicular hormones have permanent influences on reproductive behavior potentials of mammals was provided by a report published in 1959 by Phoenix, Goy, Gerall, and Young. Inspired by several isolated studies appearing in the late 1930s (Dantchakoff, 1938a,b,c), Phoenix et al. showed that the administration of testosterone to pregnant guinea pigs resulted in female offspring that displayed high levels of malelike mounting behaviors when tested in adulthood. Moreover, these females were severely impaired in their ability to perform the typical female sexual pattern. This seminal paper founded an entirely new research area within the field of behavioral endocrinology. Before that time, considerable information was available on the mechanism by which various components of sexual morphology emerged, but virtually nothing was known about the differentiation of behavior into male and female patterns.

Supported by Grant HD-04688 from the National Institute of Child Health and Human Development and by Research Scientist Development Award II 1-K2-MH00049 from the National Institute of Mental Health.

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Authors and Affiliations

  1. Department of Psychology, Villanova University, Villanova, Pennsylvania, 19085, USA

    Ingeborg L. Ward & O. Byron Ward

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  1. Ingeborg L. Ward
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  2. O. Byron Ward
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Editors and Affiliations

  1. Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Norman Adler

  2. Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York, USA

    Donald Pfaff

  3. Wisconsin Regional Primate Research Center, Madison, Wisconsin, USA

    Robert W. Goy

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© 1985 Plenum Press, New York

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Ward, I.L., Ward, O.B. (1985). Sexual Behavior Differentiation. In: Adler, N., Pfaff, D., Goy, R.W. (eds) Reproduction. Handbook of Behavioral Neurobiology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4832-0_4

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  • DOI: https://doi.org/10.1007/978-1-4684-4832-0_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4834-4

  • Online ISBN: 978-1-4684-4832-0

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