Morphology of Human Renal Cystic Disease

  • Jay Bernstein


This chapter contains a discussion of certain morphologic features of autosomal dominant, adult polycystic kidney disease (APKD) in relation to current theories of pathogenesis. The principal theories are (1) obstruction of tubular lumina by epithelial hyperplasia and (2) increased compliance of tubular walls secondary to an abnormality in the tubular basement membrane.


Renal Cyst Cystic Disease Epithelial Hyperplasia Cystic Kidney Tubular Basement Membrane 
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Jay Bernstein
    • 1
  1. 1.Department of Anatomic PathologyWilliam Beaumont HospitalRoyal OakUSA

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