Thoracic Duct Drainage
Allograft rejection continues to be the major obstacle to obtaining a successful graft in spite of significant strides having been made in the areas of histocompatibility, organ preservation, and immunosuppression. At the Veterans Administration Medical Center and the Vanderbilt University Medical Center in Nashville, we have used thoracic duct drainage (TDD) as a means of immunologically preparing a select group of patients for transplantation. This report presents our clinical experience with this therapeutic modality during the past 10 years.
KeywordsThoracic Duct Chronic Active Hepatitis Viral Encephalitis Veteran Administration Medical Lymphocyte Depletion
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- 4.Murray JE, Wilson RE, Tilney NL, Merrill JP, Cooper WC, Birth AG, Carpenter CB, Hager EB, Dammin GJ, Harrison JH: Five years’ experience in renal transplantation with immunosuppressive drugs: Survival, function, complications, and the role of lymphocyte depletion by thoracic duct fistula. Ann Surg 168:416, 1968.PubMedCrossRefGoogle Scholar
- 5.Fish JC, Sarles HE, Remmers AR, Tyson KRT, Canales CO, Beathard GA, Fukushima M, Ritzmann SE, Levin WC: Circulating lymphocyte depletion in preparation for renal allotransplantation. Surg Gyn Obstet 128:777, 1969.Google Scholar