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Protein Utilization in Chronic Renal Insufficiency in Children

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Chronic Renal Disease

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Abstract

It is obvious that at least some of the toxic compounds responsible for uremia are metabolic products of protein catabolism. There is also ample evidence that protein metabolism is significantly altered in children with chronic renal insufficiency (Delaporte et al., 1976, 1978; Conley et al., 1980; Holliday et al., 1970; Grupe, 1981b). These studies, coupled with the empiric demonstration that low-protein diets alleviate many of the symptoms of uremia, have led to a precept that has now become axiomatic: stipulating low-protein intake in chronic renal insufficiency. There is, however, the rational goal of reducing the main dietary sources of hydrogen ion, phosphate, potassium, and sulfate to the lowest possible level commensurate with the patient’s renal function.

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Author information

Authors and Affiliations

  1. Division of Nephrology, The Children’s Hospital, Boston, Massachusetts, 02115, USA

    Warren E. Grupe, Nancy S. Spinozzi & William E. Harmon

Authors
  1. Warren E. Grupe
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  2. Nancy S. Spinozzi
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  3. William E. Harmon
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Editor information

Editors and Affiliations

  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. National Institutes of Health, Bethesda, Maryland, USA

    Nancy Boucot Cummings M.D.

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© 1985 Plenum Publishing Corporation

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Grupe, W.E., Spinozzi, N.S., Harmon, W.E. (1985). Protein Utilization in Chronic Renal Insufficiency in Children. In: Cummings, N.B., Klahr, S. (eds) Chronic Renal Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4826-9_31

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  • DOI: https://doi.org/10.1007/978-1-4684-4826-9_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4828-3

  • Online ISBN: 978-1-4684-4826-9

  • eBook Packages: Springer Book Archive

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