Immunology in Genesis of Partial and Total Hydatidiform Mole

  • Shoshichi Takeuchi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 176)


In early pregnancy, a variety of pathology of trophoblastic cells is observed in trophoblastic disease and in spontaneous abortion. Trophoblastic disease includes hydatidiform mole, metastatic and/or invasive mole, and choriocarcinoma. Therefore, for better understanding of trophoblastic disease and spontaneous abortion, an exact knowledge of the morbid anatomy of trophoblasts is required. Especially needed is profound insight into regulatory mechanisms of in vivo trophoblastic growth which may undergo either damage or proliferation and survival. But the regulatory mechanisms are not clear because of their complexity, involving cellular factors such as benign or malignant neoplastic cellular changes, and/or environmental factors such as nutritional, endocrinological, and immunological factors.


Chromosomal Anomaly Spontaneous Abortion Myometrial Invasion Hydatidiform Mole Total Mole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Shoshichi Takeuchi
    • 1
  1. 1.Department of Obstetrics and GynecologySchool of Medicine Niigata UniversityNiigataJapan

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