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The Study and Treatment of Gestational Trophoblastic Diseases at the Brewer Trophoblastic Disease Center, 1962 – 1979

  • John R. Lurain
  • John I. Brewer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 176)

Abstract

The John I. Brewer Trophoblastic Disease Center of Northwestern University Medical School was founded in 1962 for the study and treatment of gestational trophoblastic diseases. From 1962 to 1984, the Center has received referrals of 4,461 patients from 42 states and 7 foreign countries. Experience gained at the Center in the management of these patients provides the basis for this report. Only patients managed at the Center up to 1979 are analyzed here in order to provide for five-year follow-up (1).

Keywords

Ectopic Pregnancy Metastatic Site Spontaneous Regression Chorionic Villus Hydatidiform Mole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Lurain, J. R., Brewer, J. I., Torok, E. E., and Halpern, B., Gestational trophoblastic disease: treatment results at the Brewer Trophoblastic Disease Center,Obstet. Gynecol. 60: 354 (1982).Google Scholar
  2. 2.
    Lurain, J. R., Brewer, J. I., Mazur, M. T., and Torok, E. E., Fatal gestational trophoblastic disease: an analysis of treatment failures, Amer. J. Obstet. Gynecol. 144: 391 (1982).Google Scholar
  3. 3.
    Mazur, M. T., Lurain, J. R., and Brewer, J. I., Fatal gestational choriocarcinoma. Clinicopathologic study of patients treated at a trophoblastic disease center, Cancer 50: 1833 (1982).PubMedCrossRefGoogle Scholar
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    Sand, P. K., Lurain, J. R., and Brewer, J. I., Repeat gestational trophoblastic disease, Obstet. Gynecol. 63: 140 (1983).Google Scholar
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    Lurain, J. R., Brewer, J. I., Torok, E. E., and Halpern, B., Natural history of hydatidiform mole after primary evacuation, Amer. J. Obstet. Gynecol. 145: 591 (1983).Google Scholar
  6. 6.
    Brewer, J. I., Torok, E. E., Kahan, B. D., Stanhope, C. R., and Halpern, B., Gestational trophoblastic disease: origin of choriocarcinoma, invasive mole and choriocarcinoma associated with hydatidiform mole, and some immunologic aspects, Adv. Cancer Res. 27: 89 (1978).CrossRefGoogle Scholar
  7. 7.
    Brewer, J. I., and Mazur, M. T., Gestational choriocarcinoma. Its origin in the placenta during seemingly normal pregnancy, Amer. J. Surg. Pathol. 5: 267 (1981).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • John R. Lurain
    • 1
  • John I. Brewer
    • 1
  1. 1.The John I. Brewer Trophoblastic Disease Center Department of Obstetrics and Gynecology, and Cancer CenterNorthwestern University Medical School and Northwestern Memorial HospitalChicagoUSA

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