The Role of Regional Centers for Gestational Trophoblastic Disease
The concept of establishing regional centers for the management of patients with gestational trophoblastic disease (GTD) evolved as a direct result of the success of the program established by Dr. Roy Hertz at the National Cancer Institute. A number of individuals trained in the field of obstetrics and gynecology emerged from the clinical fellowship program at that institution who recognized that they had both an obligation and an opportunity to create in their own academic centers the type of facility which had functioned so well on a national level for over 10 years. Decentralization, as it were, would at the same time make available this new therapeutic modality to the largest number of patients and provide an adequate source of material for expanded clinical and laboratory research and teaching programs.
KeywordsLocal Resection Blastic Disease Hydatidiform Mole Single Agent Chemotherapy Gestational Trophoblastic Disease
Unable to display preview. Download preview PDF.
- 1.Goldstein, D. P., Prevention of gestational trophoblastic disease by use of actinomycin D in molar pregnancies, Obstet. Gynecol. 43: 475 (1974).Google Scholar
- 2.Goldstein, D. P., and Berkowitz, R.S., “Gestational Trophoblastic Neoplasms - Clinical Principles of Diagnosis and Management,” W. B. Saunders Company, Philadelphia, 1982.Google Scholar
- 4.Goldstein, D. P., Berkowitz, R. S., and Cohen, S. M., The current management of molar pregnancy, Curr. Probl. Obstet. Gynecol. 3: 1 (1979).Google Scholar
- 6.Berkowitz, R. S., Goldstein, D. P., Marean, A. R., and Bernstein, M. R., Oral contraceptives and postmolar trophoblastic disease, Obstet. Gynecol. 58: 474 (1981).Google Scholar
- 7.Goldstein, D. P., and Berkowitz, R. S., The management of gestational trophoblastic neoplasms, Curr. Probl. Obstet. Gynecol. 3: 1 (1980).Google Scholar
- 9.Berkowitz, R. S., and Goldstein, D. P., Methotrexate with citrovorum factor rescue and non-metastatic gestational trophoblastic neoplasms, Obstet. Gynecol. 54: 725 (1979).Google Scholar
- 16.Shirley, R. L., Goldstein, D. P., and Collins, J. J., Jr., The role of thoracotomy in the management of patients with chest metastases from gestational trophoblastic disease, J. Thor. Cardio. Surg. 63: 545 (1972).Google Scholar
- 17.Brace, K. C., The role of irradiation in the treatment of metastatic trophoblastic disease, Radiology 91: 540 (1968).Google Scholar
- 18.Hammond, C. B., Weed, J. C., Jr., and Currie, J. L., The role of operation in the current therapy of gestational trophoblastic disease, Amer. J. Obstet. Gynecol. 136: 844 (1980).Google Scholar
- 19.Pastorfide, G. B., and Goldstein, D. P., Pregnancy after hydatidiform mole, Obstet. Gynecol. 42: 67 (1973).Google Scholar
- 20.Goldstein, D. P., Berkowitz, R. S., and Bernstein, M. R., Reproductive performance after molar pregnancy and gestational trophoblastic tumors, Clin. Obstet. Gynecol. 27: 221 (1984).Google Scholar
- 21.Federschneider, J. M., Goldstein, D. P., Berkowitz, R. S., Marean, A. R., and Bernstein, M. R., Natural history of recurrent molar pregnancy, Obstet. Gynecol. 55: 457 (1980).Google Scholar