Epidemiology of Trophoblast Disease in Africa — Lagos
Trophoblast neoplasm is a common disease in Nigeria and this has been confirmed by previous workers (1, 2, 3). Choriocarcinoma is the third most common cancer in Nigeria, after cancer of the cervix and of the breast. Having realized the significance of this tumor, which fortunately is invariably curable if treated promptly, much attention is now focused on its epidemiology. Although racial incidence of this disease is undisputed, its etiology has in the past been linked with external factors including viral (4), chemical (5), dietary (6, 7), and genetic (8, 9). It has also been suggested (9) that trophoblastic neoplasms may be attributed to immune mechanisms.
KeywordsFolinic Acid Parity Distribution Hydatidiform Mole Gestational Trophoblastic Disease Trophoblast Neoplasm
Unable to display preview. Download preview PDF.
- 2.Ogunbode, O., Benign hydatidiform mole in Ibadan, Nigeria, Int. J. Gynecol. Obstet. 15:387 (1978).Google Scholar
- 6.Javey, H. and Sajadi, H., Hydatidiform mole in southern Iran: a statistical survey of 113 cases, Int. J. Gynecol. Obstet.15: 390 (1978).Google Scholar
- 7.Novak, E. R. and Woodruff, J.D., “Gynaecologic and Obstetric Pathology,” Edition 7, W. B. Saunders, Philadelphia (1974), p. 599.Google Scholar
- 10.W.H.O. Special program of research, development and research training in human reproduction: task force on gestational trophoblastic disease (1979)(Unpublished).Google Scholar
- 11.Makokha, A. E. and Mati, J. K. G., Choriocarcinoma at Kenyatta National Hospital, 1973–79, J. Obstet. Gynecol. East Cent. Africa 1:27 (1982).Google Scholar