Parathyroid Hormone (PTH) Status and Phosphate (Pi) Transport in Proximal Brush Border Membrane Vesicles (BBMV) and Whole Kidney
PTH and dietary Pi are independent factors which influence the tubular Pi reabsorptive capacity as assessed by determining the maximal tubular reabsorption of Pi per volume of glomerular filtrate (max. TRPi/ml GF) (1). Both factors can also alter the Na+-dependent Pi transport system located in the luminal membrane of the proximal tubule (2, 3). In the situation of Pi restriction, plasma PTH level is markedly decreased as compared to normal Pi feeding (4).
KeywordsBrush Border Membrane Vesicle Luminal Membrane Renal Brush Border Membrane Renal Cortical Slice Renal Brush Border Membrane Vesicle
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- 4.Freudiger, H., Caverzasio, J., Fischer, J., Trechsel, U. and Bonjour, J.P., Urinary cyclic AMP and parathyroid hormone status in rats with intact and reduced renal mass. Manuscript in preparation.Google Scholar