Modification of the Renal Effects of Ouabain by Calcium Channel Blockers

  • Manuel A. Cruz-Soto
  • Manuel Martínez-Maldonado
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)


Ouabain, a specific inhibitor of Na+K+ ATPase, has been shown to inhibit renin release and exert natriuretic and renal vasoconstrictive effects in the dog (1, 2, 3, 4).


Glomerular Filtration Rate Renal Artery Mean Arterial Pressure Calcium Channel Blocker Renal Blood Flow 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Manuel A. Cruz-Soto
    • 1
  • Manuel Martínez-Maldonado
    • 1
  1. 1.Renal Metabolic Laboratory, Medical and Research Service Veterans Administration Center and the Department of Medicine and PhysiologyUniversity of Puerto Rico School of MedicineSan JuanPuerto Rico

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