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Interactions between Mg and Blood Pressure

  • Kai Lau
  • Claire Oasa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 178)

Abstract

The relationship between magnesium and blood pressure has been sought, evaluated and studied in considerable depth both in the intact animal and at the level of the various organs involved. In the simplest form, three potential interactions are possible (Table 1). Although new insights have been gained regarding the acute effects of Mg loading or withdrawal on muscle cell excitability-contraction coupling, the contractile process and energy metabolism, present knowledge is still inadequate to establish the first form of interaction, viz. whether changes in Mg metabolism would produce sustained alterations in blood pressure in the intact but complex animal, endowed with all the physiologic counterregulatory and/or adaptive mechanisms. Bluntly put, the role of disturbances in Mg homeostasis, if any, has not been sufficiently defined in the pathogenesis and/or maintenance of hypertension.

Keywords

Magnesium Sulfate Systemic Blood Pressure Federation Proceeding Magnesium Salt Ganglionic Blockade 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Kai Lau
    • 1
  • Claire Oasa
    • 1
  1. 1.Division of Nephrology Department of Internal MedicineThe University of MichiganAnn ArborUSA

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